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Surprising Science

Gene Therapy Breakthrough

Scientists at New York University have combined two methods that scientists use to carry D.N.A. into cell nuclei. The result could help analyze proteins and ultimately improve gene therapy.

Sometimes two things work better together than alone. “Seiichi Yamano, assistant professor in the Department of Prosthodontics at N.Y.U.’s College of Dentistry, and Jin Kim Montclare, who runs N.Y.U.-Poly’s Protein Engineering and Molecular Design Lab, have developed a remarkably effective way to combine two methods that scientists use as vehicles to carry D.N.A. into cell nuclei. The result could help understand gene function, analyze proteins and ultimately improve gene therapy for a number of genetic diseases like hemophilia and muscular dystrophy, acquired diseases like cancer, neurodegenerative diseases like A.L.S., as well as H.I.V. and hepatitis.”


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